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Make the planet GRADE again! - 13 September 2017

POSTED BY POSTED IN Company News, GRADE methodology | No Comments

We invite you to take a look at “Make the planet GRADE again” action ( #gradeplanet @grade_planet). Recent global political situation (as racist attacs), as well as the changing position of science that faces quasi-scientific theories (e.g. antivaccine campaigns), prompts us to sign under the manifesto that points the reset of common sense in public space. We are a part of the world, for which education and respect for the environment and the other man is a basic value. Integral element of this concern is the effort to improve medical care in the world. Although obvious for many, barriers to achieve health and well-being often arise from ignorance. But we have also become accustomed to health care guidelines based on verified available studies. In the context of current scientific consciousness the standard is GRADE and it is irresponsible although possible that some would take a step back to the pre-GRADE era. The GRADE Working Group’s brainstorms, the Cochrane Collaboration efforts, and activity of several centers around the world that develop software for making guidelines and systematic reviews prove that there is still room for action throughout our community to strengthen GRADE consciousness and disseminate GRADE tools.

We feel ourselves very much the part of GRADE planet. Join us at and Global Evidence Summit 2017


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Let’s meet at Global Evidence Summit! - 05 September 2017

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The Evidence Prime team is very excited to be attending the Global Evidence Summit in Cape Town. The synergy of effort from the annual Cochrane Collaboration Colloquium and the G-I-N conference will certainly provide some interesting meeting opportunities. Zbyszek and Eric will be happy to meet all those who would like to know more about our solutions. If you do not see those gentlemen in the crowd, please write to, or tweet out to @evidence_prime and we will certainly arrange a meeting.
We are already familiar with the excellent program of the conference. Out of the labyrinth of lectures, discussions, workshops and presentations we provide here a list of GRADE events. The most experienced GRADE experts will explain the basics, and also point out some new directions and new applications to which the GRADE methodology may be applied. There will be very hands-on activities on specific issues, which will facilitate and improve the quality of your work in systematic reviews and guideline development. Those who are still undecided about which events to attend in Cape Town should definitely look into one of these meetings:

Monday, 11 September 2017

9:00 to 16:00
Developing GRADE guidance for overviews of systematic reviews

Wednesday, 13 September 2017

11:00 to 12:30
Integrating GRADE network meta-analysis SoF tables in network meta-analysis reports

14:00 to 15:30
Assessing confidence in qualitative evidence used in guidelines: Benefits and challenges when applying GRADE-CERQual

16:00 to 17:30
Uptake and Implementation of GRADE among guideline developers in the United States

Thursday, 14 September 2017

11:00 to 12:30
Presentation of time-to-event outcomes in GRADE Summary of Finding (SOF) tables: Evaluation of Cochrane Cancer Reviews

Confidence in qualitative synthesized findings: A principled and pragmatic critique of ConQual and GRADE-CERQual

Applying the GRADE-CERQual approach: Experiences from the development of an EPOC qualitative-evidence synthesis

14:00 to 15:30
The GRADE-CERQual approach for assessing how much confidence to place in findings from qualitative evidence syntheses

Friday, 15 September 2017

11:00 to 12:30
Making the GRADE approach for network meta-analysis more efficient

Saturday, 16 September 2017

11.00 to 12.30
GRADE approach for determining certainty of evidence on how patients value outcomes

Creating evidence tables for use in systematic reviews and guideline development: GRADE approach

Systematic reviews of prognostic studies V: Using GRADE to appraise bodies of evidence about overall prognosis and prognostic factors

14:00 to 15:30
Using GRADE to integrate randomized and non-randomized studies in systematic reviews

Using GRADE in public-health guidelines – challenges and some solutions?

Assessing the certainty of the evidence from network-meta analysis using the GRADE approach

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Are any alternatives for evidence based medicine? - 27 June 2017

POSTED BY POSTED IN General analyses | No Comments

GRADEpro is the software of choice for experts who care about the highest quality of evidence and the most reliable sources in medical science. Of course a lot of ‘scientists’ still prefer some alternative approaches. As summer vacation begins for many of us, let us recall the clever recap Seven alternatives to evidence based medicine” by David Isaacs and Dominic Fitzgerald in BMJ. This witty article was written almost decade ago, but we find its relevance very much alive today:

(1) Eminence based medicine – when doctors have a touching faith in clinical experience, which has been defined as “making the same mistakes with increasing confidence over an impressive number of years.”

 (2) Vehemence based medicine – The substitution of volume for evidence is an effective technique for brow beating your more timorous colleagues and for convincing relatives of your ability.

(3) Eloquence based medicine – Sartorial elegance and verbal eloquence are powerful substitutes for evidence.

(4) Providence based medicine – If the caring practitioner has no idea of what to do next, the decision may be best left in the hands of the Almighty.

(5) Diffidence based medicine – Some doctors see a problem and look for an answer. Others merely see a problem. The diffident doctor may do nothing from a sense of despair.

(6) Nervousness based medicine – Fear of litigation is a powerful stimulus to overinvestigation and overtreatment.

(7) Confidence based medicine – restricted to surgeons. In the table there are more details: marker – bravado, measuring device – sweat test, unit of measurement – no sweat.

This bright classification was supplemented by Aldo Mariotto with the term:

(8) Propaganda based medicine, that is connected with pharmaceutical representatives’ influence on physicians.

… we can’t find any culminating point, just use GRADEing!